Epigenetic Clocks: How DNA Methylation Can Estimate a Person's Age
Standard forensic DNA profiling can tell investigators an enormous amount about identity, but it has never been able to answer one particular question directly: how old is this person? Two people can share remarkably similar STR profiles in terms of basic genetic markers while being decades apart in actual age, since standard identity-focused DNA testing simply wasn't designed to capture that kind of information. A newer area of forensic genetics, built around something called DNA methylation, is changing that, allowing genetic material itself to reveal a surprisingly accurate estimate of someone's actual age. This represents one of forensic genetics' more genuinely fascinating recent frontiers, since it works through an entirely different biological mechanism than the genetic sequence variation that standard DNA profiling relies upon. What DNA Methylation Actually Is Beyond the Genetic Code Itself DNA methylation refers to a specific type of chemical modif...